AVATAR AD includes four Avatar instruments
AVATAR
System
Finally, an incubator designed specifically for the cultivation of primary human cells
The AVATAR System lets you fine-tune oxygen and pressure levels to cater culture conditions to your cell type of interest. Customizing settings based on tumor type or native microenvironment allows cells to behave as they would in vivo
the human microenvironment is hypoxic and pressurized
The human body is made up of diverse microenvironments that influence the behavior and molecular profiles of cells
Tissues are hypoxic and pressurized. They function at a much lower oxygen level than the basic air environment in typical CO2 incubator, and interstitial fluid pressures vary depending on the tissue and organ type
model the tumor microenvironment with
the avatar system
Only AVATAR lets you regulate and alter both the atmospheric pressure and oxygen concentration to what’s optimal for your cell type and research
Modulation of pressure & oxygen has profound effects on cell homeostasis
Oxygen and pressure have distinct physiological effects and both play important but independent roles in the human microenvironment. Under hypoxic and pressurized culturing conditions, changes are seen in cell morphology, gene and protein expression. Modulation of atmospheric pressure affects the mechanobiology of cell function during culture, and has profound effects on cell homeostasis and metabolism
Study how cells respond under physiological culture conditions
Cells under pressure: The AVATAR system can regulate pressure settings to alter gene and protein expression profiles of cells
Users all over the world have adopted the AVATAR System
AVATAR
System
tumor environment modeling
Identify novel checkpoint inhibitors that work effectively under immunosuppressive tumor microenvironments
stem cell differentiation
Enhance iPSC reprogramming & stem cell differentiation efficiency
cell therapy optimization
Enhance CAR-T potency, persistence & homing
organoid research
Generate organoids and spheroids that thrive under hypoxic culture conditions