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AVATAR

System

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The AVATAR™ Cell Control System lets you fine-tune oxygen and pressure to cater culture conditions to your cell type of interest. Customizing settings based on tumor type or native microenvironment allows cells to behave as they would in vivo.

 

So you can now study cells under a range of conditions and find out which combination of factors is ideal for each type of cell. Because AVATAR mimics a more relevant human microenvironment, cells stay happy and healthy too.

the human microenvironment is hypoxic and pressurized

Oxygen and pressure have distinct physiological effects and both play important but independent roles in the human microenvironment. Under hypoxic and pressurized culturing conditions, changes are seen in cell morphology, gene and protein expression. Modulation of atmospheric pressure affects the mechanobiology of cell function during culture, and has profound effects on cell homeostasis and metabolism.

The human body is made up of diverse microenvironments that influence the behavior and molecular profiles of cells. Tissues are hypoxic and pressurized. They function at a much lower oxygen level than the basic air environment in typical CO2 incubator, and interstitial fluid pressures vary depending on the tissue and organ type.

tumor environment modeling

Identify novel checkpoint inhibitors that work effectively under immunosuppressive tumor microenvironments

stem cell differentiation

Enhance iPSC reprogramming & stem cell differentiation efficiency

cell therapy optimization

Enhance CAR-T potency, persistence & homing

 

 

 

organoid research

Generate organoids and spheroids that thrive under hypoxic culture conditions

model the tumor microenvironment with

the avatar system

Oxygen and pressure have distinct physiological effects and both play important but independent roles in the human microenvironment. Under hypoxic and pressurized culturing conditions, changes are seen in cell morphology, gene and protein expression. Modulation of atmospheric pressure affects the mechanobiology of cell function during culture, and has profound effects on cell homeostasis and metabolism.

The human body is made up of diverse microenvironments that influence the behavior and molecular profiles of cells. Tissues are hypoxic and pressurized. They function at a much lower oxygen level than the basic air environment in typical CO2 incubator, and interstitial fluid pressures vary depending on the tissue and organ type.

Study how cells respond under physiological culture conditions

Oxygen and pressure have distinct physiological effects and both play important but independent roles in the human microenvironment. Under hypoxic and pressurized culturing conditions, changes are seen in cell morphology, gene and protein expression. Modulation of atmospheric pressure affects the mechanobiology of cell function during culture, and has profound effects on cell homeostasis and metabolism.

The human body is made up of diverse microenvironments that influence the behavior and molecular profiles of cells. Tissues are hypoxic and pressurized. They function at a much lower oxygen level than the basic air environment in typical CO2 incubator, and interstitial fluid pressures vary depending on the tissue and organ type.

model the tumor microenvironment with

the avatar system

Study how cells respond under physiological culture conditions

Cells under pressure: The AVATAR system can regulate pressure settings to alter gene and protein expression profiles of cells

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