Engineer, Evaluate, and Manufacture.

The AVATAR™ platform brings physiologically relevant tumor microenvironment (TME) control
into cell therapy workflows, improving potency, persistence, and predictability for solid tumor therapies.

Explore the Technology

Microenvironment-Driven Manufacturing.

Integrate physiologic oxygen and pressure control directly into GMP workflows to train cells for environments they face in vivo.

Seamless R&D → GMP Continuity.

Our platforms share identical environmental profiles and formats, reducing technical transfer risk and accelerating translation.

Closed, Automated Scale-Up.

Reproducible yields and consistent phenotypes supported by closed, automated workflows designed for manufacturing.

TME-Informed Potency Insights.

Generate real-time, label-free potency data under physiologically relevant conditions to inform faster, more predictive decisions.

From Discovery to Clinical Manufacturing

A single, continuous platform designed to optimize cell therapy potency at every stage offering development

ODYSSEY

FOUNDRY

R&D & PD Optimization

Refine activation, expansion, and phenotype using precise oxygen and pressure control in small-scale, cost-effective workflows.
Identify the exact environmental parameters that drive maximum potency during process development.

Explore ODYSSEY

Clinical & Commercial Manufacturing

Automated, scalable workflows bring metabolic conditioning into clinical and commercial production
Maintain biological consistency from lab to clinic while enhancing potency and persistence at scale

Explore FOUNDRY

Explore AI

Quantify killing kinetics under physiologically relevant environments to evaluate function earlier and more accurately
Machine-learning models enable rapid potency assessment and deep insight into therapeutic performance

Functional Evaluation

Validated by Leaders in Cell & Gene Therapy

Setting a new standard for solid tumor cell therapy development.

The Phenotype That Persists

Selective expansion of Tcm and Tscm populations associated with efficacy.

Sustained Killing Power

Persistent cytotoxicity through repeated tumor challenges under harsh TME conditions easy.

Built for Existing GMP workflow

Drop-in compatibility enables faster deployment with lower infrastructure costs.

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AVATAR™ Expanded CAR T cells are 70% More Potent in TME Conditions

AVATAR
CAR T cells

Conventional

CAR T cells

% Cytotoxicity

Hypoxia, high interstitial pressure, and immunosuppressive proteins create a hostile microenvironment pH for therapeutic cells

Conventional incubation systems fail to prepare cells for this reality which results in early exhaustion, poor in vivo performance, and limited clinical success

Cell therapies produced in small-scale quantities face the problem of emulating those conditions in separate GMP manufacturing systems